ProSci

CD83 Antibody [Michel17] (PE)

Product Code:
 
PSI-76-318
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rat
Antibody Isotype:
 
Rat IgG1
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
Michel17
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Flow Cytometry
Storage:
 
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
 

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CodeSizePrice
PSI-76-318-0.025mg0.025mg£373.00
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Further Information

Additional Names:
Cd83, Cd83
Background:
The Michel-17 monoclonal antibody specifically reacts with mouse CD83, a 45kDA type I transmembrane glycoprotein. CD83 is expressed mainly on activated lymphocytes and mature dendritic cells and it plays a role in T cell development. The Michel-17 antibody does not induce an activation signal on dendritic or T cells.
Background References:
  • Cramer, S. O., Trumpfheller, C., Mehlhoop, U., Mor, S., Fleischer, B., von Bonin, A. (2000). Activation-induced expression of murine CD83 on T cells and identification of a specific CD83 ligand on murine B cells.International immunology,12(9), 1347-1351.
  • Wolenski, M., Cramer, S. O., Ehrlich, S., Steeg, C., Fleischer, B., Von Bonin, A. (2003). Enhanced Activation of CD83Positive T Cells*.Scandinavian journal of immunology,58(3), 306-311.
  • Breloer, M., Fleischer, B. (2008). CD83 regulates lymphocyte maturation, activation and homeostasis.Trends in immunology,29(4), 186-194.
Buffer:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Conjugate:
PE
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
12522
NCBI Official Name:
CD83 antigen
NCBI Official Symbol:
Cd83
NCBI Organism:
Mus musculus
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Area:
Innate Immunity
SPECIFICITY:
The Michel-17 monoclonal antibody specifically reacts with mouse CD83, a 45kDA type I transmembrane glycoprotein.
Swissprot #:
O88324
User NOte:
Optimal dilutions for each application to be determined by the researcher.