ProSci

CD31 Antibody [390]

Product Code:
 
PSI-76-167
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rat
Antibody Isotype:
 
Rat IgG2a, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
390
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Applications:
  • Flow Cytometry
  • Functional Study
Storage:
 
The product should be stored undiluted at 4°C. Do not freeze.
 

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PSI-76-167-0.5mg0.5mg£686.00
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Further Information

Additional Names:
Cd31, Pecam, C85791, PECAM-1, Pecam1
Background:
The 390 monoclonal antibody specifically reacts with mouse cd31, a 130-140 kDA type I transmembrane glycoprotein also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1). CD31 is reported to bind to CD38 and is expressed on platelets, monocytes, granulocytes, and endothelial cells. It plays a role in angiogenesis, wound healing, cellular migration, and signal transduction.
Background References:
  • HORENSTEIN, A., STOCKINGER, H., Imhof, B., MALAVASI, F. (1998). CD38 binding to human myeloid cells is mediated by mouse and human CD31.Biochem. J,330, 1129-1135.
  • Baldwin, H. S., Shen, H. M., Yan, H. C., DeLisser, H. M., Chung, A., Mickanin, C., ... Albelda, S. M. (1994). Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31): alternatively spliced, functionally distinct isoforms expressed during mammalian cardiovascular development.Development,120(9), 2539-2553.
  • DeLisser, H. M., Christofidou-Solomidou, M., Strieter, R. M., Burdick, M. D., Robinson, C. S., Wexler, R. S., ... Albelda, S. M. (1997). Involvement of endothelial PECAM-1/CD31 in angiogenesis.The American journal of pathology,151(3), 671.
Buffer:
Phosphate-buffered aqueous solution, ph7.2.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
18613
NCBI Official Name:
platelet/endothelial cell adhesion molecule 1
NCBI Official Symbol:
Pecam1
NCBI Organism:
Mus musculus
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/?g of the protein.
Research Area:
Cancer,Functional Assays
SPECIFICITY:
The 390 monoclonal antibody specifically reacts with mouse cd31, a 130-140 kDA type I transmembrane glycoprotein also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1).
Swissprot #:
Q08481
User NOte:
Optimal dilutions for each application to be determined by the researcher.