ProSci

TLR4/MD-2 Complex Antibody [MTS510]

Product Code:
 
PSI-77-017
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rat
Antibody Isotype:
 
Rat IgG2a, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
MTS510
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Applications:
  • Flow Cytometry
  • Functional Study
Storage:
 
The product should be stored undiluted at 4°C. Do not freeze.
 

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CodeSizePrice
PSI-77-017-0.05mg0.05mg£469.00
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Further Information

Additional Names:
Lps, Ly87, Ran/M1, Rasl2-8, Tlr4
Background:
The MTS510 monoclonal antibody specifically reacts with the Toll-Like Receptor 4 (TLR-4) and MD-2 (LY96) molecular complex. The complex of TLR-4, MD-2, and CD14 regulates the innate immune system recognition of bacterial lipopolysaccharides (LPS) and is expressed on the surface of thioglycollate-elicited macrophages. The epitope that binds the MTS510 antibody is lost after LPS stimulation and the antibody can be used to co-immunoprecipitates MD-2 and TLR4.
Buffer:
Phosphate-buffered aqueous solution, ph7.2.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
21898
NCBI Official Name:
toll-like receptor 4
NCBI Official Symbol:
Tlr4
NCBI Organism:
Mus musculus
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/?g of the protein.
Research Area:
Innate Immunity
SPECIFICITY:
The MTS510 monoclonal antibody specifically reacts with the Toll-Like Receptor 4 (TLR-4) and MD-2 (LY96) molecular complex.
Swissprot #:
Q9QUK6
User NOte:
Optimal dilutions for each application to be determined by the researcher.