Product Code:
AG-25T-0120
Antibody Clonality:
Polyclonal
Applications:- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
Short Tem: +4°C Long Term: -20°C
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This product comes from:
Switzerland.
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7-10 working days.
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Further Information
Alternate Names/Synonyms:
Solute Carrier Family 7 Member 8; Lat2; L-type Amino Acid Transporter 2; Large Neutral Amino Acids Transporter Small Subunit 2
0.5mg/ml
32160000
liquid
Liquid. In PBS containing 1mg/ml BSA and 0.02% sodium azide.
Avoid freeze/thaw cycles.
Synthetic peptide corresponding to a partial sequence of mouse Slc7a8 (Q9QXW9).
Polyclonal Antibody. Recognizes mouse and human Slc7a8. Other species not tested.Detects a ~50kDa Slc7a8 band in wild type mouse brain, kidney, jejunum, ileum and other tissues, which is absent in knock-out animals. In some tissues the antibody detects an additional unknown 38kDa band. Source: Rabbit. Applications: IHC, WB. Liquid. In PBS containing 1mg/ml BSA and 0.02% sodium azide. L-type amino acid transporter (LAT) family members are Na(+)-independent transporters, which deliver neutral amino acids into cells. The four LATs, LAT1 (SLC7A5), LAT2 (SLC7A8), LAT3 (SLC43A1) and LAT4 (SLC43A2) are responsible for the majority of cellular leucine uptake. They show increased expression in many cancers and are critical for control of protein translation and cell growth through the mTORC1 pathway. The increased transporter expression observed in cancers is regulated by transcriptional pathways such as hormone receptors, c-myc and nutrient starvation responses.
Q9QXW9
Plastic Vial
L-type amino acid transporter (LAT) family members are Na(+)-independent transporters, which deliver neutral amino acids into cells. The four LATs, LAT1 (SLC7A5), LAT2 (SLC7A8), LAT3 (SLC43A1) and LAT4 (SLC43A2) are responsible for the majority of cellular leucine uptake. They show increased expression in many cancers and are critical for control of protein translation and cell growth through the mTORC1 pathway. The increased transporter expression observed in cancers is regulated by transcriptional pathways such as hormone receptors, c-myc and nutrient starvation responses.
Antigen affinity purified.
Rabbit
Recognizes mouse and rat Slc7a8. Detects a ~50kDa Slc7a8 band in wild type mouse brain, kidney, jejunum, ileum and other tissues, which is absent in knock-out animals. In some tissues the antibody detects an additional unknown 38kDa band.
Non-hazardous
Primary Antibodies
12352203
Stable for at least 1 year after receipt when stored at -20°C.