ProSci

MYCN Antibody

Product Code:
 
PSI-62-879
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western Blot at 1:1000 dilution + CCRF-CEM whole cell lysate Lysates/proteins at 20 ug per lane.
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Western Blot at 1:1000 dilution + CCRF-CEM whole cell lysate Lysates/proteins at 20 ug per lane.

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PSI-62-879-400ul400ul£626.00
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Further Information

Additional Names:
N-myc proto-oncogene protein, Class E basic helix-loop-helix protein 37, bHLHe37, MYCN, BHLHE37, NMYC
Application Note:
For WB starting dilution is: 1:1000
Background:
MYCN is a member of the MYC family and a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of its gene is associated with a variety of tumors, most notably neuroblastomas.
Background References:
  • Combaret,V., Pediatr Blood Cancer 53 (3), 329-331 (2009)
  • Alvarez-Rodriguez,R., J. Cell. Sci. 122 (PT 5), 595-599 (2009)
  • Jacobs,J.F., BMC Cancer 9, 239 (2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This MYCN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-351 amino acids from the C-terminal region of human MYCN.
NCBI Gene ID #:
4613
NCBI Official Name:
N-myc proto-oncogene protein
NCBI Official Symbol:
MYCN
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
50 kDa
Protein Accession #:
P04198
Protein GI Number:
127604
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cancer
Swissprot #:
P04198
User NOte:
Optimal dilutions for each application to be determined by the researcher.