ProSci

MCC Antibody

Product Code:
 
PSI-59-060
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in U937 cell line lysates (35ug/lane).
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Western blot analysis in U937 cell line lysates (35ug/lane).

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PSI-59-060-400ul400ul£626.00
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Further Information

Additional Names:
Colorectal mutant cancer protein, Protein MCC, MCC
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene.
Background References:
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010)
  • Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010)
  • Arnaud, C., et al. FEBS Lett. 583(14):2326-2332(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MCC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 473-501 amino acids from the Central region of human MCC.
NCBI Gene ID #:
4163
NCBI Official Name:
Colorectal mutant cancer protein
NCBI Official Symbol:
MCC
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
93 kDa
Protein Accession #:
P23508
Protein GI Number:
317373352
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer
Swissprot #:
P23508
User NOte:
Optimal dilutions for each application to be determined by the researcher.