Further Information
Ribosomal protein S6 kinase beta-1, S6K-beta-1, S6K1, 70 kDa ribosomal protein S6 kinase 1, P70S6K1, p70-S6K 1, Ribosomal protein S6 kinase I, Serine/threonine-protein kinase 14A, p70 ribosomal S6 kinase alpha, p70 S6 kinase alpha, p70 S6K-alpha, p70 S6KA, RPS6KB1, STK14A
For WB starting dilution is: 1:1000
RPS6KB1 is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding the gene for RPS6KB1 and overexpression of this kinase are seen in some breast cancer cell lines.
- Adem, C., et al., Genes Chromosomes Cancer 41(1):1-11 (2004).
- Suzuki, Y., et al., Genome Res. 14(9):1711-1718 (2004).
- Gomez-Cambronero, J., et al., Leuk. Res. 28(7):755-762 (2004).
- Raught, B., et al., EMBO J. 23(8):1761-1769 (2004).
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rabbit, Rat
This S6K (RPS6KB1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 405-434 amino acids from human S6K (RPS6KB1).
6198
Ribosomal protein S6 kinase beta-1
RPS6KB1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
59 kDa
P23443
54041234
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cancer,Cell Cycle,Obesity,Neuroscience,Signal Transduction
P23443
Optimal dilutions for each application to be determined by the researcher.