ProSci

PPP1CC Antibody

Product Code:
 
PSI-58-851
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
1 / 2
Western blot analysis in WiDr cell line lysates (35ug/lane).
2 / 2
Western blot analysis of PPP1CC using rabbit polyclonal PPP1CC Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PPP1CC gene.
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Western blot analysis in WiDr cell line lysates (35ug/lane).
Western blot analysis of PPP1CC using rabbit polyclonal PPP1CC Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PPP1CC gene.

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PSI-58-851-400ul400ul£626.00
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Further Information

Additional Names:
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit, PP-1G, Protein phosphatase 1C catalytic subunit, PPP1CC
Application Note:
For WB starting dilution is: 1:1000
Background:
Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca(2+)/calmodulin dependent protein kinase II.
Background References:
  • Lee, J.H., et al. J. Biol. Chem. 285(32):24466-24476(2010)
  • Kuzmin, A., et al. Biol. Reprod. 81(2):319-326(2009)
  • Fujiki, R., et al. Nature 459(7245):455-459(2009)
  • Rogne, M., et al. Hum. Mol. Genet. 18(5):978-987(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen:
This PPP1CC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-309 amino acids from the C-terminal region of human PPP1CC.
NCBI Gene ID #:
5501
NCBI Official Name:
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
NCBI Official Symbol:
PPP1CC
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
37 kDa
Protein Accession #:
P36873
Protein GI Number:
548573
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Obesity,Neuroscience,Signal Transduction
Swissprot #:
P36873
User NOte:
Optimal dilutions for each application to be determined by the researcher.