Antibody Isotype:
Rabbit Ig
Antibody Clonality:
Polyclonal
Applications:- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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![Western blot analysis in NCI-H460 cell line lysates (35ug/lane). Western blot analysis in NCI-H460 cell line lysates (35ug/lane).](https://www.prosci-inc.com/static-images/57-214_1.jpg)
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![SYT1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. SYT1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.](https://www.prosci-inc.com/static-images/57-214_2.jpg)
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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- Further Information
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Further Information
Synaptotagmin-1, Synaptotagmin I, SytI, p65, SYT1, SVP65, SYT
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
The synaptotagmins are integral membrane proteins of
synaptic vesicles thought to serve as Ca(2+) sensors in the process
of vesicular trafficking and exocytosis. Calcium binding to
synaptotagmin-1 participates in triggering neurotransmitter release
at the synapse (Fernandez-Chacon et al., 2001 [PubMed
11242035]).
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Musch, M.W., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 298 (2), G203-G211 (2010) :
- Kathir, K.M., et al. Biochim. Biophys. Acta 1798(2):297-302(2010)
- Pattaro, C., et al. BMC Med. Genet. 11, 41 (2010) :
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Monkey, Mouse, Rat
This SYT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 349-377 amino acids from the C-terminal region of human SYT1.
6857
Synaptotagmin-1
SYT1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
48 kDa
P21579
135086
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cancer,Neuroscience,Signal Transduction
P21579
Optimal dilutions for each application to be determined by the researcher.