Antibody Isotype:
Rabbit Ig
Antibody Clonality:
Polyclonal
Application:
Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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- Further Information
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Further Information
Acetyl-CoA carboxylase 1, ACC1, ACC-alpha, Biotin carboxylase, ACACA, ACAC, ACC1, ACCA
For WB starting dilution is: 1:1000
Acetyl-CoA carboxylase (ACC) is a complex multifunctional
enzyme system. ACC is a biotin-containing enzyme which catalyzes
the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting
step in fatty acid synthesis. There are two ACC forms, alpha and
beta, encoded by two different genes. ACC-alpha is highly enriched
in lipogenic tissues. The enzyme is under long term control at the
transcriptional and translational levels and under short term
regulation by the phosphorylation/dephosphorylation of targeted
serine residues and by allosteric transformation by citrate or
palmitoyl-CoA. Multiple alternatively spliced transcript variants
divergent in the 5' sequence and encoding distinct isoforms have
been found for this gene.
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Kim, C.W., et al. Proc. Natl. Acad. Sci. U.S.A. 107(21):9626-9631(2010)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
This ACACA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2010-2039 amino acids from the C-terminal region of human ACACA.
31
Acetyl-CoA carboxylase 1
ACACA
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
266 kDa
Q13085
118601083
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cancer,Obesity,Signal Transduction
Q13085
Optimal dilutions for each application to be determined by the researcher.