ProSci

CYP11A1 Antibody

Product Code:
 
PSI-63-278
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis of anti-CYP11A1 Antibody in HepG2 cell line lysates (35ug/lane).
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Western blot analysis of anti-CYP11A1 Antibody in HepG2 cell line lysates (35ug/lane).

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PSI-63-278-400ul400ul£626.00
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Further Information

Additional Names:
Cholesterol side-chain cleavage enzyme, mitochondrial, CYPXIA1, Cholesterol desmolase, Cytochrome P450 11A1, Cytochrome P450(scc), CYP11A1, CYP11A
Application Note:
For WB starting dilution is: 1:1000
Background:
CYP11A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones.
Background References:
  • Celhar,T., Cancer Genet. Cytogenet. 187 (1), 28-33 (2008)
  • Morales,A., Pancreas 37 (2), 165-169 (2008)
  • Shigematsu,K., Eur. J. Endocrinol. 158 (6), 867-878 (2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Monkey
Immunogen:
This CYP11A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-120 amino acids from the N-terminal region of human CYP11A1.
NCBI Gene ID #:
1583
NCBI Official Name:
Cholesterol side-chain cleavage enzyme, mitochondrial
NCBI Official Symbol:
CYP11A1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
60 kDa
Protein Accession #:
P05108
Protein GI Number:
143811381
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cancer,Obesity,Signal Transduction
Swissprot #:
P05108
User NOte:
Optimal dilutions for each application to be determined by the researcher.