ProSci

CPT1B Antibody

Product Code:
 
PSI-58-668
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in SK-BR-3 cell line lysates (35ug/lane).
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Western blot analysis in SK-BR-3 cell line lysates (35ug/lane).

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PSI-58-668-400ul400ul£626.00
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Further Information

Additional Names:
Carnitine O-palmitoyltransferase 1, muscle isoform, CPT1-M, Carnitine O-palmitoyltransferase I, muscle isoform, CPT I, CPTI-M, Carnitine palmitoyltransferase 1B, Carnitine palmitoyltransferase I-like protein, CPT1B, KIAA1670
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene.
Background References:
  • Matsuo, T., et al. Biochem. Genet. 48 (3-4), 193-201 (2010) :
  • Miljkovic, I., et al. Obesity (Silver Spring) 17(7):1396-1401(2009)
  • Miyagawa, T., et al. PLoS ONE(4), E5394 (2009) :
  • van der Leij, F.R., et al. J. Biol. Chem. 277(30):26994-27005(2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CPT1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 744-770 amino acids from the C-terminal region of human CPT1B.
NCBI Gene ID #:
1375
NCBI Official Name:
Carnitine O-palmitoyltransferase 1, muscle isoform
NCBI Official Symbol:
CPT1B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
88 kDa
Protein Accession #:
Q92523
Protein GI Number:
2493497
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity,Signal Transduction
Swissprot #:
Q92523
User NOte:
Optimal dilutions for each application to be determined by the researcher.