Further Information
Trifunctional enzyme subunit beta, mitochondrial, TP-beta, 3-ketoacyl-CoA thiolase, Acetyl-CoA acyltransferase, Beta-ketothiolase, HADHB
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
HADHB encodes the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. Mutations in this gene result in trifunctional protein deficiency. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation.
- Purevsuren, J., et al. Mol. Genet. Metab. 98(4):372-377(2009)
- Bogenhagen, D.F., et al. J. Biol. Chem. 283(6):3665-3675(2008)
- Wang, R., et al. Zhonghua Fu Chan Ke Za Zhi 41(10):672-675(2006)
- Hillier, L.W., et al. Nature 434(7034):724-731(2005)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Bovine, Monkey
This HADHB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 315-342 amino acids from the C-terminal region of human HADHB.
3032
Trifunctional enzyme subunit beta, mitochondrial
HADHB
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
51 kDa
P55084
116241345
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cancer,Obesity,Signal Transduction
P55084
Optimal dilutions for each application to be determined by the researcher.