Further Information
Platelet-derived growth factor receptor alpha, PDGF-R-alpha, PDGFR-alpha, Alpha platelet-derived growth factor receptor, Alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A, CD140a antigen, Platelet-derived growth factor alpha receptor, Platelet-derived growth factor receptor 2, PDGFR-2, CD140a, PDGFRA, PDGFR2, RHEPDGFRA
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
PDGFRA is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.
- Wilczynski, S.P., et al., Hum. Pathol. 36(3):242-249 (2005).
- Hiwatari, M., et al., Leukemia 19(3):476-477 (2005).
- Debiec-Rychter, M., et al., Gastroenterology 128(2):270-279 (2005).
- Sakurai, S., et al., Hum. Pathol. 35(10):1223-1230 (2004).
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Mouse, Rat
This PDGFRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 746-775 amino acids from human PDGFRA.
5156
Platelet-derived growth factor receptor alpha
PDGFRA
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
123 kDa
P16234
129892
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cancer,Signal Transduction
P16234
Optimal dilutions for each application to be determined by the researcher.