Further Information
Thioredoxin reductase 1, cytoplasmic, TR, 1.8.1.9, Gene associated with retinoic and interferon-induced mortality 12 protein, GRIM-12, Gene associated with retinoic and IFN-induced mortality 12 protein, KM-102-derived reductase-like factor, Thioredoxin reductase TR1, TXNRD1, GRIM12, KDRF
For WB starting dilution is: 1:2000
Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.
- Gasdaska P.Y.,et al.FEBS Lett. 373:5-9(1995).
- Koishi R.,et al.J. Biol. Chem. 272:2570-2577(1997).
- Hofman E.R.,et al.Mol. Cell. Biol. 18:6493-6504(1998).
- Rundloef A.-K.,et al.Free Radic. Biol. Med. 36:641-656(2004).
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Bovine, Pig
This TXNRD1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 271-305 amino acids from the Central region of human TXNRD1.
7296
Thioredoxin reductase 1, cytoplasmic
TXNRD1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
71 kDa
Q16881
172046253
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cell Cycle,Obesity,Signal Transduction
Q16881
Optimal dilutions for each application to be determined by the researcher.