Further Information
DNA damage-inducible transcript 3 protein, DDIT-3, C/EBP zeta, C/EBP-homologous protein, CHOP, C/EBP-homologous protein 10, CHOP-10, CCAAT/enhancer-binding protein homologous protein, Growth arrest and DNA damage-inducible protein GADD153, DDIT3, CHOP, CHOP10, GADD153
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
This gene encodes a member of the CCAAT/enhancer-binding
protein (C/EBP) family of transcription factors. The protein
functions as a dominant-negative inhibitor by forming heterodimers
with other C/EBP members, such as C/EBP and LAP (liver activator
protein), and preventing their DNA binding activity. The protein is
implicated in adipogenesis and erythropoiesis, is activated by
endoplasmic reticulum stress, and promotes apoptosis. Fusion of
this gene and FUS on chromosome 16 or EWSR1 on chromosome 22
induced by translocation generates chimeric proteins in myxoid
liposarcomas or Ewing sarcoma. Multiple alternatively spliced
transcript variants encoding two isoforms with different length
have been identified.
- Park, S.H., et al. J. Immunol. 185(9):5522-5530(2010)
- Goodall, J.C., et al. Proc. Natl. Acad. Sci. U.S.A. 107(41):17698-17703(2010)
- Zhang, H.M., et al. J. Virol. 84(17):8446-8459(2010)
- Cazanave, S.C., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 299 (1), G236-G243 (2010) :
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
This DDIT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-110 amino acids from the Central region of human DDIT3.
1649
DNA damage-inducible transcript 3 protein
DDIT3
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
19 kDa
P35638
544022
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cell Cycle,Obesity,Signal Transduction
P35638
Optimal dilutions for each application to be determined by the researcher.