Further Information
Macrophage-stimulating protein receptor, MSP receptor, CDw136, Protein-tyrosine kinase 8, p185-Ron, CD136, Macrophage-stimulating protein receptor alpha chain, Macrophage-stimulating protein receptor beta chain, MST1R, PTK8, RON
For WB starting dilution is: 1:1000
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).
- Maggiora, P., et al., Exp. Cell Res. 288(2):382-389 (2003).
- Santoro, M.M., et al., Dev. Cell 5(2):257-271 (2003).
- Penengo, L., et al., Oncogene 22(24):3669-3679 (2003).
- Zhou, Y.Q., et al., Oncogene 22(2):186-197 (2003).
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
This RON antibody is generated from rabbits immunized with two KLH conjugated synthetic peptides between 22-51 amino and 1370-1400 acids from the N-terminal and C-terminal regions of human RON.
4486
Macrophage-stimulating protein receptor
MST1R
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
152 kDa
Q04912
294862462
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Cell Cycle,Signal Transduction
Q04912
Optimal dilutions for each application to be determined by the researcher.