ProSci

CLK2 Antibody

Product Code:
 
PSI-58-679
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in HL-60 cell line lysates (35ug/lane).
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Western blot analysis in HL-60 cell line lysates (35ug/lane).

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PSI-58-679-400ul400ul£626.00
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Further Information

Additional Names:
Dual specificity protein kinase CLK2, CDC-like kinase 2, CLK2
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the CLK family of dual specificity protein kinases. CLK family members have been shown to interact with, and phosphorylate, serine- and arginine-rich (SR) proteins of the spliceosomal complex, which is a part of the regulatory mechanism that enables the SR proteins to control RNA splicing. Note that this gene is distinct from TELO2 gene (GeneID:9894), which shares CLK2 and hCLK2 symbol aliases in common with this gene, but encodes a protein that is involved in telomere length regulation.
Background References:
  • Nam, S.Y., et al. J. Biol. Chem. 285(41):31157-31163(2010)
  • Eisenreich, A., et al. Circ. Res. 104(5):589-599(2009)
  • Rendtlew Danielsen, J.M., et al. J. Biol. Chem. 284(7):4140-4147(2009)
  • Castle, J.C., et al. Nat. Genet. 40(12):1416-1425(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This CLK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-319 amino acids from the Central region of human CLK2.
NCBI Gene ID #:
1196
NCBI Official Name:
Dual specificity protein kinase CLK2
NCBI Official Symbol:
CLK2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
60 kDa
Protein Accession #:
P49760
Protein GI Number:
1705919
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Signal Transduction
Swissprot #:
P49760
User NOte:
Optimal dilutions for each application to be determined by the researcher.