ProSci

GRIA3 Antibody

Product Code:
 
PSI-57-436
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in WiDr cell line lysates (35ug/lane).
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Western blot analysis in WiDr cell line lysates (35ug/lane).

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PSI-57-436-400ul400ul£626.00
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Further Information

Additional Names:
Glutamate receptor 3, GluR-3, AMPA-selective glutamate receptor 3, GluR-C, GluR-K3, Glutamate receptor ionotropic, AMPA 3, GluA3, GRIA3, GLUR3, GLURC
Application Note:
For WB starting dilution is: 1:1000
Background:
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.
Background References:
  • Ripka, S., et al. Neoplasia 12(8):659-667(2010)
  • Liu, Q., et al. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 26(4):376-378(2010)
  • Feyissa, A.M., et al. Prog. Neuropsychopharmacol. Biol. Psychiatry 34(2):279-283(2010)
  • Marek, G.J., et al. Mol. Pharmacol. 77(3):317-326(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Monkey, Mouse, Rat
Immunogen:
This GRIA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-217 amino acids from the N-terminal region of human GRIA3.
NCBI Gene ID #:
2892
NCBI Official Name:
Glutamate receptor 3
NCBI Official Symbol:
GRIA3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
101 kDa
Protein Accession #:
P42263
Protein GI Number:
77416864
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
P42263
User NOte:
Optimal dilutions for each application to be determined by the researcher.