Antibody Isotype:
Rabbit Ig
Antibody Clonality:
Polyclonal
Application:
Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
No additional charges, what you see is what you pay! *
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available!
Contact us to find what you can save.
This product comes from:
United States.
Typical lead time:
14-21 working days.
Contact us for more accurate information.
- Further Information
- Documents
- Show All
Further Information
Sialidase-1, Acetylneuraminyl hydrolase, G9 sialidase, Lysosomal sialidase, N-acetyl-alpha-neuraminidase 1, NEU1, NANH
For WB starting dilution is: 1:1000
The protein encoded by this gene is a lysosomal enzyme
that cleaves terminal sialic acid residues from substrates such as
glycoproteins and glycolipids. In the lysosome, this enzyme is part
of a heterotrimeric complex together with beta-galactosidase and
cathepsin A (the latter is also referred to as 'protective
protein'). Mutations in this gene can lead to sialidosis, a
lysosomal storage disease that can be type 1 (cherry red
spot-myoclonus syndrome or normosomatic type), which is late-onset,
or type 2 (the dysmorphic type), which occurs at an earlier age
with increased severity.
- Caciotti, A., et al. J. Neurol. 256(11):1911-1915(2009)
- Bonten, E.J., et al. J. Biol. Chem. 284(41):28430-28441(2009)
- Barcellos, L.F., et al. PLoS Genet.(10), E1000696 (2009) :
- Wang, J., et al. J. Neurochem. 111(2):547-554(2009)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Bovine
This NEU1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-214 amino acids from the Central region of human NEU1.
4758
Sialidase-1
NEU1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
45 kDa
Q99519
17368612
This antibody is purified through a protein A column, followed by peptide affinity purification.
Obesity,Signal Transduction
Q99519
Optimal dilutions for each application to be determined by the researcher.