ProSci

DHODH Antibody

Product Code:
 
PSI-60-535
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in K562 cell line lysates (35ug/lane).
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Western blot analysis in K562 cell line lysates (35ug/lane).

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PSI-60-535-400ul400ul£626.00
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Further Information

Additional Names:
Dihydroorotate dehydrogenase (quinone), mitochondrial, DHOdehase, Dihydroorotate oxidase, DHODH
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane.
Background References:
  • Hail, N. Jr., et al. Free Radic. Biol. Med. 49(1):109-116(2010)
  • Ng, S.B., et al. Nat. Genet. 42(1):30-35(2010)
  • Grabar, P.B., et al. Ann. Rheum. Dis. 68(8):1367-1368(2009)
  • Pawlik, A., et al. Pharmacogenomics 10(2):303-309(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This DHODH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-194 amino acids from the Central region of human DHODH.
NCBI Gene ID #:
1723
NCBI Official Name:
Dihydroorotate dehydrogenase (quinone), mitochondrial
NCBI Official Symbol:
DHODH
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
43 kDa
Protein Accession #:
Q02127
Protein GI Number:
56405372
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q02127
User NOte:
Optimal dilutions for each application to be determined by the researcher.