ProSci

MPI Antibody

Product Code:
 
PSI-58-940
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in U251 cell line lysates (35ug/lane).
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Western blot analysis in U251 cell line lysates (35ug/lane).

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PSI-58-940-400ul400ul£626.00
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Further Information

Additional Names:
Mannose-6-phosphate isomerase, Phosphohexomutase, Phosphomannose isomerase, PMI, MPI, PMI1
Application Note:
For WB starting dilution is: 1:1000
Background:
Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib.
Background References:
  • Johnatty, S.E., et al. PLoS Genet.(7), E1001016 (2010) :
  • Lamesch, P., et al. Genomics 89(3):307-315(2007)
  • Xiao, J., et al. J. Mol. Graph. Model. 25(3):289-295(2006)
  • Vuillaumier-Barrot, S., et al. J. Med. Genet. 39(11):849-851(2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This MPI antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human MPI.
NCBI Gene ID #:
4351
NCBI Official Name:
Mannose-6-phosphate isomerase
NCBI Official Symbol:
MPI
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
47 kDa
Protein Accession #:
P34949
Protein GI Number:
462567
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
P34949
User NOte:
Optimal dilutions for each application to be determined by the researcher.