ProSci

DAO Antibody

Product Code:
 
PSI-57-366
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in Jurkat cell line lysates (35ug/lane).
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Western blot analysis in Jurkat cell line lysates (35ug/lane).

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PSI-57-366-400ul400ul£626.00
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Further Information

Additional Names:
D-amino-acid oxidase, DAAO, DAMOX, DAO, DAO, DAMOX
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known; it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia.
Background References:
  • Kim, B., et al. Psychiatry Res 179(2):121-125(2010)
  • Caldinelli, L., et al. Protein Sci. 19(8):1500-1512(2010)
  • Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)
  • Ohnuma, T., et al. Schizophr. Res. 118 (1-3), 300-302 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This DAO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-287 amino acids from the Central region of human DAO.
NCBI Gene ID #:
1610
NCBI Official Name:
D-amino-acid oxidase
NCBI Official Symbol:
DAO
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
39 kDa
Protein Accession #:
P14920
Protein GI Number:
25453448
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
P14920
User NOte:
Optimal dilutions for each application to be determined by the researcher.