Further Information
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial, 533-, ECH1
For WB starting dilution is: 1:1000
This gene encodes a member of the hydratase/isomerase
superfamily. The gene product shows high sequence similarity to
enoyl-coenzyme A (CoA) hydratases of several species, particularly
within a conserved domain characteristic of these proteins. The
encoded protein, which contains a C-terminal peroxisomal targeting
sequence, localizes to the peroxisome. The rat ortholog, which
localizes to the matrix of both the peroxisome and mitochondria,
can isomerize 3-trans,5-cis-dienoyl-CoA to
2-trans,4-trans-dienoyl-CoA, indicating that it is a
delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in
the auxiliary step of the fatty acid beta-oxidation pathway.
Expression of the rat gene is induced by peroxisome proliferators.
- Olsen, J.V., et al. Cell 127(3):635-648(2006)
- Olsen, J.V., et al. Cell 127(3):635-648(2006)
- Kovalyov, L.I., et al. Biochemistry Mosc. 71(4):448-453(2006)
- Goehler, H., et al. Mol. Cell 15(6):853-865(2004)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
This ECH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-250 amino acids from the C-terminal region of human ECH1.
1891
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial
ECH1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
36 kDa
Q13011
82654933
This antibody is purified through a protein A column, followed by peptide affinity purification.
Obesity,Signal Transduction
Q13011
Optimal dilutions for each application to be determined by the researcher.