ProSci

NT5M Antibody

Product Code:
 
PSI-61-197
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western Blot at 1:2000 dilution Lane 1: human liver lysate Lane 2: RPMI-8226 whole cell lysate Lane 3: SH-SY5Y lysate Lysates/proteins at 20 ug per lane.
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Western Blot at 1:2000 dilution Lane 1: human liver lysate Lane 2: RPMI-8226 whole cell lysate Lane 3: SH-SY5Y lysate Lysates/proteins at 20 ug per lane.

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PSI-61-197-200ul200ul£626.00
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Further Information

Additional Names:
5'(3')-deoxyribonucleotidase, mitochondrial, 5',3'-nucleotidase, mitochondrial, 3.1.3.-, Deoxy-5'-nucleotidase 2, dNT-2, NT5M, DNT2
Application Note:
For WB starting dilution is: 1:2000
Background:
Dephosphorylates specifically the 5' and 2'(3')- phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP.
Background References:
  • Rampazzo C.,et al.Proc. Natl. Acad. Sci. U.S.A. 97:8239-8244(2000).
  • Rinaldo-Matthis A.,et al.Nat. Struct. Biol. 9:779-787(2002).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This NT5M antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 195-226 amino acids from human NT5M.
NCBI Gene ID #:
56953
NCBI Official Name:
5'(3')-deoxyribonucleotidase, mitochondrial
NCBI Official Symbol:
NT5M
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
26 kDa
Protein Accession #:
Q9NPB1
Protein GI Number:
38258255
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q9NPB1
User NOte:
Optimal dilutions for each application to be determined by the researcher.