Further Information
Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial, Isocitric dehydrogenase subunit gamma, NAD(+)-specific ICDH subunit gamma, IDH3G
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the gamma subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. This gene is a candidate gene for periventricular heterotopia.
- Bzymek, K.P., et al. Biochemistry 46(18):5391-5397(2007)
- Soundar, S., et al. J. Biol. Chem. 281(30):21073-21081(2006)
- Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)
- Weiss, C., et al. Biochemistry 39(7):1807-1816(2000)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Bovine, Monkey
This IDH3G antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 366-393 amino acids from the C-terminal region of human IDH3G.
3421
Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial
IDH3G
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
43 kDa
P51553
1708404
This antibody is purified through a protein A column, followed by peptide affinity purification.
Obesity,Signal Transduction
P51553
Optimal dilutions for each application to be determined by the researcher.