Antibody Isotype:
Rabbit Ig
Antibody Clonality:
Polyclonal
Applications:- Fluorescence-activated cell sorting (FACS)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
1 / 5
![Western Blot at 1:1000 dilution + human liver lysate Lysates/proteins at 20 ug per lane. Western Blot at 1:1000 dilution + human liver lysate Lysates/proteins at 20 ug per lane.](https://www.prosci-inc.com/static-images/57-922_1.jpg)
2 / 5
![Western Blot at 1:1000 dilution + human liver lysate Lysates/proteins at 20 ug per lane. Western Blot at 1:1000 dilution + human liver lysate Lysates/proteins at 20 ug per lane.](https://www.prosci-inc.com/static-images/57-922_2.jpg)
3 / 5
![](https://www.prosci-inc.com/static-images/57-922_3.jpg)
4 / 5
![Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with *ALDH6A1 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with *ALDH6A1 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.](https://www.prosci-inc.com/static-images/57-922_4.jpg)
5 / 5
![Flow cytometric analysis of ATDC5 cells using ALDH6A1 Antibody (N-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Flow cytometric analysis of ATDC5 cells using ALDH6A1 Antibody (N-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.](https://www.prosci-inc.com/static-images/57-922_5.jpg)
❮❯No additional charges, what you see is what you pay! *
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available!
Contact us to find what you can save.
This product comes from:
United States.
Typical lead time:
14-21 working days.
Contact us for more accurate information.
- Further Information
- Documents
- Show All
Further Information
Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial, MMSDH, Malonate-semialdehyde dehydrogenase [acylating], Aldehyde dehydrogenase family 6 member A1, ALDH6A1, MMSDH
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
ALDH6A1 belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. This protein is a mitochondrial methylmalonate semialdehyde dehydrogenase, and catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.
- Kuiper,H., Cytogenet. Genome Res. 109 (4), 533 (2005)
- Anderson,N.L., Mol. Cell Proteomics(4), 311-326 (2004)
- Chambliss,K.L., J. Inherit. Metab. Dis. 23 (5), 497-504 (2000)
- Kedishvili,N.Y., J. Biol. Chem. 267 (27), 19724-19729 (1992)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
This ALDH6A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-59 amino acids from the N-terminal region of human ALDH6A1.
4329
Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial
ALDH6A1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
58 kDa
Q02252
12643424
This antibody is purified through a protein A column, followed by peptide affinity purification.
Obesity,Signal Transduction
Q02252
Optimal dilutions for each application to be determined by the researcher.