ProSci

Guanylyl Cyclase beta 1 Antibody

Product Code:
 
PSI-63-445
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis of anti-GUCY1B3 Pab(AP8171b) in Y79 cell line lysate.
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Western blot analysis of anti-GUCY1B3 Pab(AP8171b) in Y79 cell line lysate.

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PSI-63-445-400ul400ul£626.00
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Further Information

Additional Names:
Guanylate cyclase soluble subunit beta-1, GCS-beta-1, Guanylate cyclase soluble subunit beta-3, GCS-beta-3, Soluble guanylate cyclase small subunit, GUCY1B3, GUC1B3, GUCSB3, GUCY1B1
Application Note:
For WB starting dilution is: 1:1000
Background:
Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha and a beta subunit, catalyzes the conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs.
Background References:
  • Russwurm, M., et al., J. Biol. Chem. 276(48):44647-44652 (2001).
  • Lucas, K.A., et al., Pharmacol. Rev. 52(3):375-414 (2000).
  • Papapetropoulos, A., et al., J. Cell. Physiol. 167(2):213-221 (1996).
  • Giuili, G., et al., Hum. Genet. 91(3):257-260 (1993).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GUCY1B3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected between 589-619 amino acids of human GUCY1B3.
NCBI Gene ID #:
2983
NCBI Official Name:
Guanylate cyclase soluble subunit beta-1
NCBI Official Symbol:
GUCY1B3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
71 kDa
Protein Accession #:
Q02153
Protein GI Number:
399328
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Signal Transduction
Swissprot #:
Q02153
User NOte:
Optimal dilutions for each application to be determined by the researcher.