ProSci

HPS3 Antibody

Product Code:
 
PSI-58-778
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in T47D cell line lysates (35ug/lane).
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Western blot analysis in T47D cell line lysates (35ug/lane).

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PSI-58-778-400ul400ul£626.00
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Further Information

Additional Names:
Hermansky-Pudlak syndrome 3 protein, HPS3
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a protein containing a potential clathrin-binding motif, consensus dileucine signals, and tyrosine-based sorting signals for targeting to vesicles of lysosomal lineage. The encoded protein may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 3. Alternate splice variants exist, but their full length sequence has not been determined. [provided by RefSeq].
Background References:
  • Torres-Serrant, M., et al. J. Pediatr. Hematol. Oncol. 32(6):448-453(2010)
  • Huizing, M., et al. Platelets 18(2):150-157(2007)
  • Santiago Borrero, P.J., et al. J. Invest. Dermatol. 126(1):85-90(2006)
  • Boissy, R.E., et al. Am. J. Pathol. 166(1):231-240(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This HPS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-290 amino acids from the N-terminal region of human HPS3.
NCBI Gene ID #:
84343
NCBI Official Name:
Hermansky-Pudlak syndrome 3 protein
NCBI Official Symbol:
HPS3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
114 kDa
Protein Accession #:
Q969F9
Protein GI Number:
20532121
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q969F9
User NOte:
Optimal dilutions for each application to be determined by the researcher.