ProSci

SPRY4 Antibody

Product Code:
 
PSI-62-914
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis of anti-SPRY4 Antibody in Sk-Br-3 cell line lysates (35ug/lane)
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Western blot analysis of anti-SPRY4 Antibody in Sk-Br-3 cell line lysates (35ug/lane)

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PSI-62-914-400ul400ul£626.00
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Further Information

Additional Names:
Protein sprouty homolog 4, Spry-4, SPRY4
Application Note:
For WB starting dilution is: 1:1000
Background:
SPRY4 is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. The protein is positioned upstream of RAS activation and impairs the formation of active GTP-RAS.
Background References:
  • Tsai CF, et al. (2008)Proteome Res
  • Guo A, et al. (2008) Proc Natl Acad SciS105, 692-7
  • Rikova K, et al. (2007) Cell 131, 1190-203
  • Wolf-Yadlin A, Hautaniemi S, Lauffenburger DA, White FM (2007) Proc Natl Acad SciS104, 5860-5
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SPRY4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-301 amino acids from the C-terminal region of human SPRY4.
NCBI Gene ID #:
81848
NCBI Official Name:
Protein sprouty homolog 4
NCBI Official Symbol:
SPRY4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
33 kDa
Protein Accession #:
Q9C004
Protein GI Number:
14916719
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9C004
User NOte:
Optimal dilutions for each application to be determined by the researcher.