Further Information
Charged multivesicular body protein 5, Chromatin-modifying protein 5, SNF7 domain-containing protein 2, Vacuolar protein sorting-associated protein 60, Vps60, hVps60, CHMP5, C9orf83, SNF7DC2
For WB starting dilution is: 1:1000
CHMP5 belongs to the chromatin-modifying protein/charged
multivesicular body protein (CHMP) family. These proteins are
components of ESCRT-III (endosomal sorting complex required for
transport III), a complex involved in degradation of surface
receptor proteins and formation of endocytic multivesicular bodies
(MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular
distributions, and one such CHMP, CHMP1A (MIM 164010), is required
for both MVB formation and regulation of cell cycle progression
(Tsang et al., 2006 [PubMed 16730941]).
- Wang, H.R., et al. Zhongguo Shi Yan Xue Ye Xue Za Zhi 16(2):282-285(2008)
- Row, P.E., et al. J. Biol. Chem. 282(42):30929-30937(2007)
- Huang, H.H., et al. Zhongguo Shi Yan Xue Ye Xue Za Zhi 15(4):738-742(2007)
- Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Mouse, Rat
This CHMP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-204 amino acids from the C-terminal region of human CHMP5.
51510
Charged multivesicular body protein 5
CHMP5
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
25 kDa
Q9NZZ3
51702157
This antibody is purified through a protein A column, followed by peptide affinity purification.
Signal Transduction
Q9NZZ3
Optimal dilutions for each application to be determined by the researcher.