ProSci

TFAP2A Antibody

Product Code:
 
PSI-60-706
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis of TFAP2A Antibody in NCI-H460 cell line lysates (35ug/lane)
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Western blot analysis of TFAP2A Antibody in NCI-H460 cell line lysates (35ug/lane)

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PSI-60-706-400ul400ul£626.00
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Further Information

Additional Names:
Transcription factor AP-2-alpha, AP2-alpha, AP-2 transcription factor, Activating enhancer-binding protein 2-alpha, Activator protein 2, AP-2, TFAP2A, AP2TF, TFAP2
Application Note:
For WB starting dilution is: 1:1000
Background:
TFAP2A is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. TFAP2A is the only AP-2 protein required for early morphogenesis of the lens vesicle.
Background References:
  • Provenzano,M.J., Exp. Mol. Pathol. 83 (2), 277-282 (2007)
  • Tan,Y.R., Biochem. J. 405 (1), 131-137 (2007)
  • Liu,H., EMBO Rep.(4), 394-400 (2007)
  • Han,S., J. Biol. Chem. 282 (11), 7961-7972 (2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This TFAP2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 407-436 amino acids from the C-terminal region of human TFAP2A.
NCBI Gene ID #:
7020
NCBI Official Name:
Transcription factor AP-2-alpha
NCBI Official Symbol:
TFAP2A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
48 kDa
Protein Accession #:
P05549
Protein GI Number:
135302
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Swissprot #:
P05549
User NOte:
Optimal dilutions for each application to be determined by the researcher.