ProSci

PIGT Antibody

Product Code:
 
PSI-58-317
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in NCI-H292 cell line lysates (35ug/lane).
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Western blot analysis in NCI-H292 cell line lysates (35ug/lane).

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PSI-58-317-400ul400ul£626.00
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Further Information

Additional Names:
GPI transamidase component PIG-T, Phosphatidylinositol-glycan biosynthesis class T protein, PIGT
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is an essential component of the multisubunit enzyme, GPI transamidase. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins. Several transcript variants encoding different isoforms have been found for this gene.
Background References:
  • Li, H.L., et al. FEBS Lett. 580(7):1723-1728(2006)
  • Vainauskas, S., et al. J. Biol. Chem. 280(16):16402-16409(2005)
  • Ohishi, K., et al. J. Biol. Chem. 278(16):13959-13967(2003)
  • Eisenhaber, B., et al. Bioessays 25(4):367-385(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This PIGT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 392-421 amino acids from the C-terminal region of human PIGT.
NCBI Gene ID #:
51604
NCBI Official Name:
GPI transamidase component PIG-T
NCBI Official Symbol:
PIGT
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
66 kDa
Protein Accession #:
Q969N2
Protein GI Number:
44888284
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q969N2
User NOte:
Optimal dilutions for each application to be determined by the researcher.