Further Information
Serine/arginine-rich splicing factor 10, 40 kDa SR-repressor protein, SRrp40, FUS-interacting serine-arginine-rich protein 1, Splicing factor SRp38, Splicing factor, arginine/serine-rich 13A, TLS-associated protein with Ser-Arg repeats, TASR, TLS-associated protein with SR repeats, TLS-associated serine-arginine protein, TLS-associated SR protein, SRSF10, FUSIP1, FUSIP2, SFRS13A, TASR
For WB starting dilution is: 1:1000
This gene product is a member of the serine-arginine (SR)
family of proteins, which is involved in constitutive and regulated
RNA splicing. Members of this family are characterized by
N-terminal RNP1 and RNP2 motifs, which are required for binding to
RNA, and multiple C-terminal SR/RS repeats, which are important in
mediating association with other cellular proteins. This protein
can influence splice site selection of adenovirus E1A pre-mRNA. It
interacts with the oncoprotein TLS, and abrogates the influence of
TLS on E1A pre-mRNA splicing. This gene has multiple pseudogenes.
Alternative splicing of this gene results in multiple transcript
variants encoding different isoforms. In addition, transcript
variants utilizing alternative polyA sites exist.
- Manley, J.L., et al. Genes Dev. 24(11):1073-1074(2010)
- Ling, I.F., et al. Hum. Mutat. 31(6):702-709(2010)
- Shi, Y., et al. Mol. Cell 28(1):79-90(2007)
- Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Mouse
This FUSIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 197-225 amino acids from the C-terminal region of human FUSIP1.
10772
Serine/arginine-rich splicing factor 10
SRSF10
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
31 kDa
O75494
This antibody is purified through a protein A column, followed by peptide affinity purification.
O75494
Optimal dilutions for each application to be determined by the researcher.