Antibody Isotype:
Rabbit Ig
Antibody Clonality:
Polyclonal
Applications:- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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![Western blot analysis in Hela cell line lysates (35ug/lane). Western blot analysis in Hela cell line lysates (35ug/lane).](https://www.prosci-inc.com/static-images/58-053_1.jpg)
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![TNKS Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. TNKS Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.](https://www.prosci-inc.com/static-images/58-053_2.jpg)
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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Further Information
Tankyrase-1, TANK1, ADP-ribosyltransferase diphtheria toxin-like 5, ARTD5, Poly [ADP-ribose] polymerase 5A, TNKS-1, TRF1-interacting ankyrin-related ADP-ribose polymerase, Tankyrase I, TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
TNKS may regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. Has PARP activity and can modify TERF1, and thereby contribute to the regulation of telomere length.
- Hatsugai, K., et al. FEBS Lett. 584(18):3885-3890(2010)
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Olson, J.E., et al. Breast Cancer Res. Treat. (2010) In press :
- Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Mouse
This TNKS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-82 amino acids from the N-terminal region of human TNKS.
8658
Tankyrase-1
TNKS
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
142 kDa
O95271
This antibody is purified through a protein A column, followed by peptide affinity purification.
O95271
Optimal dilutions for each application to be determined by the researcher.