ProSci

CDH11 Antibody

Product Code:
 
PSI-59-952
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in mouse brain tissue lysates (35ug/lane).
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Western blot analysis in mouse brain tissue lysates (35ug/lane).

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PSI-59-952-400ul400ul£626.00
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Further Information

Additional Names:
Cadherin-11, OSF-4, Osteoblast cadherin, OB-cadherin, CDH11
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.
Background References:
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Sachdeva, M., et al. Cancer Res. 70(1):378-387(2010)
  • Canova, C., et al. Cancer Res. 69(7):2956-2965(2009)
  • Farina, A.K., et al. PLoS ONE(3), E4797 (2009) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CDH11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 622-650 amino acids from the C-terminal region of human CDH11.
NCBI Gene ID #:
1009
NCBI Official Name:
Cadherin-11
NCBI Official Symbol:
CDH11
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
88 kDa
Protein Accession #:
P55287
Protein GI Number:
146345381
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
P55287
User NOte:
Optimal dilutions for each application to be determined by the researcher.