ProSci

NEO1 Antibody

Product Code:
 
PSI-59-445
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in mouse spleen tissue lysates (35ug/lane).
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Western blot analysis in mouse spleen tissue lysates (35ug/lane).

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PSI-59-445-400ul400ul£626.00
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Further Information

Additional Names:
Neogenin, Immunoglobulin superfamily DCC subclass member 2, NEO1, IGDCC2, NGN
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a cell surface protein that is a member of the immunoglobulin superfamily. The encoded protein consists of four N-terminal immunoglobulin-like domains, six fibronectin type III domains, a transmembrane domain and a C-terminal internal domain that shares homology with the tumor suppressor candidate gene DCC. This protein may be involved in cell growth and differentiation and in cell-cell adhesion. Defects in this gene are associated with cell proliferation in certain cancers. Alternate splicing results in multiple transcript variants. [provided by RefSeq].
Background References:
  • Bradford, D., et al. J. Comp. Neurol. 518(16):3237-3253(2010)
  • Davila, S., et al. Genes Immun. 11(3):232-238(2010)
  • Zhang, A.S., et al. J. Biol. Chem. 284(34):22580-22589(2009)
  • Fujita, Y., et al. Cell Death Differ. 15(10):1593-1608(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rat
Immunogen:
This NEO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 657-685 amino acids from the Central region of human NEO1.
NCBI Gene ID #:
4756
NCBI Official Name:
Neogenin
NCBI Official Symbol:
NEO1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
160 kDa
Protein Accession #:
Q92859
Protein GI Number:
116242676
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q92859
User NOte:
Optimal dilutions for each application to be determined by the researcher.