ProSci

Mouse Dyrk1a Antibody

Product Code:
 
PSI-60-541
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the detected the Mouse Dyrk1a protein (arrow).
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Western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the detected the Mouse Dyrk1a protein (arrow).

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PSI-60-541-400ul400ul£626.00
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Further Information

Additional Names:
Dual specificity tyrosine-phosphorylation-regulated kinase 1A, Dual specificity YAK1-related kinase, MP86, Protein kinase minibrain homolog, MNBH, Dyrk1a, Dyrk
Application Note:
For WB starting dilution is: 1:1000
Background:
Dyrk1a may play a role in a signaling pathway regulating nuclear functions of cell proliferation. Phosphorylates serine, threonine and tyrosine residues in its sequence and in exogenous substrates.
Background References:
  • Park, J., et al. J. Biol. Chem. 285(41):31895-31906(2010)
  • Guo, X., et al. J. Biol. Chem. 285(17):13223-13232(2010)
  • Kurabayashi, N., et al. Mol. Cell. Biol. 30(7):1757-1768(2010)
  • Lee, Y., et al. J. Biol. Chem. 284(48):33343-33351(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This Mouse Dyrk1a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 718-745 amino acids from the C-terminal region of mouse Dyrk1a.
NCBI Gene ID #:
13548
NCBI Official Name:
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
NCBI Official Symbol:
Dyrk1a
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
85 kDa
Protein Accession #:
Q61214
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q61214
User NOte:
Optimal dilutions for each application to be determined by the researcher.