ProSci

KLF12 Antibody

Product Code:
 
PSI-58-515
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in mouse heart tissue lysates (35ug/lane).
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Western blot analysis in mouse heart tissue lysates (35ug/lane).

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PSI-58-515-400ul400ul£626.00
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Further Information

Additional Names:
Krueppel-like factor 12, Transcriptional repressor AP-2rep, KLF12, AP2REP
Application Note:
For WB starting dilution is: 1:1000
Background:
Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. The protein encoded by this gene is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Background References:
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Eyre, S., et al. Ann. Rheum. Dis. 69(7):1407-1408(2010)
  • Wieczorek, S., et al. J. Mol. Med. 88(4):413-421(2010)
  • Petersen, G.M., et al. Nat. Genet. 42(3):224-228(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This KLF12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-312 amino acids from the C-terminal region of human KLF12.
NCBI Gene ID #:
11278
NCBI Official Name:
Krueppel-like factor 12
NCBI Official Symbol:
KLF12
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
44 kDa
Protein Accession #:
Q9Y4X4
Protein GI Number:
91771555
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q9Y4X4
User NOte:
Optimal dilutions for each application to be determined by the researcher.