ProSci

CLCN2 Antibody

Product Code:
 
PSI-58-678
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in HL-60 cell line lysates (35ug/lane).
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Western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).
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Western blot analysis in HL-60 cell line lysates (35ug/lane).
Western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).

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PSI-58-678-400ul400ul£626.00
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Further Information

Additional Names:
Chloride channel protein 2, ClC-2, CLCN2
Application Note:
For WB starting dilution is: 1:1000
Background:
The transmembrane protein encoded by this gene is a voltage-gated chloride channel that maintains chloride ion homeostasis in various cells. Defects in this gene may be a cause of certain epilepsies. Four transcript variants encoding different isoforms have been found for this gene.
Background References:
  • Scheper, G.C., et al. Genet Test Mol Biomarkers 14(2):255-257(2010)
  • Cornejo, I., et al. J. Cell. Physiol. 221(3):650-657(2009)
  • Thompson, C.H., et al. J. Biol. Chem. 284(38):26051-26062(2009)
  • Kleefuss-Lie, A., et al. Nat. Genet. 41(9):954-955(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rabbit, Rat
Immunogen:
This CLCN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 209-237 amino acids from the N-terminal region of human CLCN2.
NCBI Gene ID #:
1181
NCBI Official Name:
Chloride channel protein 2
NCBI Official Symbol:
CLCN2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
99 kDa
Protein Accession #:
P51788
Protein GI Number:
288558807
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Neuroscience,Signal Transduction
Swissprot #:
P51788
User NOte:
Optimal dilutions for each application to be determined by the researcher.