ProSci

ISCU Antibody

Product Code:
 
PSI-60-893
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
1 / 2
Western blot analysis in WiDr cell line lysates (35ug/lane).
2 / 2
Western blot analysis in mouse lung tissue lysates (35ug/lane).
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Western blot analysis in WiDr cell line lysates (35ug/lane).
Western blot analysis in mouse lung tissue lysates (35ug/lane).

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PSI-60-893-400ul400ul£626.00
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Further Information

Additional Names:
Iron-sulfur cluster assembly enzyme ISCU, mitochondrial, NifU-like N-terminal domain-containing protein, NifU-like protein, ISCU, NIFUN
Application Note:
For WB starting dilution is: 1:1000
Background:
Iron-sulfur (Fe-S) clusters are necessary for several mitochondrial enzymes and other subcellular compartment proteins. They contain sulfur and iron, and are created via several steps that include cysteine desulfurases, iron donors, chaperones, and scaffold proteins. This gene encodes the two isomeric forms, ISCU1 and ISCU2, of the Fe-S cluster scaffold protein. Mutations in this gene have been found in patients with myopathy with severe exercise intolerance and myoglobinuria.
Background References:
  • Chen, Z., et al. Oncogene 29(30):4362-4368(2010)
  • Chan, S.Y., et al. Cell Metab. 10(4):273-284(2009)
  • Kollberg, G., et al. Brain 132 (PT 8), 2170-2179 (2009) :
  • Huang, J., et al. J. Biol. Inorg. Chem. 13(5):825-836(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ISCU antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-167 amino acids from the C-terminal region of human ISCU.
NCBI Gene ID #:
23479
NCBI Official Name:
Iron-sulfur cluster assembly enzyme ISCU, mitochondrial
NCBI Official Symbol:
ISCU
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
18 kDa
Protein Accession #:
Q9H1K1
Protein GI Number:
313104118
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q9H1K1
User NOte:
Optimal dilutions for each application to be determined by the researcher.