ProSci

Mouse Bmpr1a Antibody

Product Code:
 
PSI-58-516
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in SK-BR-3 cell line lysates (35ug/lane).
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Western blot analysis in SK-BR-3 cell line lysates (35ug/lane).

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PSI-58-516-400ul400ul£626.00
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Further Information

Additional Names:
Bone morphogenetic protein receptor type-1A, BMP type-1A receptor, BMPR-1A, Activin receptor-like kinase 3, ALK-3, BMP-2/BMP-4 receptor, Serine/threonine-protein kinase receptor R5, SKR5, CD292, Bmpr1a, Acvrlk3, Bmpr
Application Note:
For WB starting dilution is: 1:1000
Background:
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP-2 and BMP-4.
Background References:
  • Drogat, B., et al. Blood 116(12):2141-2151(2010)
  • Leung, A.W., et al. Dev. Dyn. 239(9):2319-2329(2010)
  • Mira, H., et al. Cell Stem Cell 7(1):78-89(2010)
  • Libusova, L., et al. Development 137(14):2297-2305(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rat
Immunogen:
This Mouse Bmpr1a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 170-197 amino acids from the Central region of mouse Bmpr1a.
NCBI Gene ID #:
12166
NCBI Official Name:
Bone morphogenetic protein receptor type-1A
NCBI Official Symbol:
Bmpr1a
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
60 kDa
Protein Accession #:
P36895
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
P36895
User NOte:
Optimal dilutions for each application to be determined by the researcher.