Further Information
V-type proton ATPase subunit H, V-ATPase subunit H, Nef-binding protein 1, NBP1, Protein VMA13 homolog, V-ATPase 50/57 kDa subunits, Vacuolar proton pump subunit H, Vacuolar proton pump subunit SFD, ATP6V1H
For WB starting dilution is: 1:1000
ATP6V1H encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes the regulatory H subunit of the V1 domain which is required for catalysis of ATP but not the assembly of V-ATPase.
- Fuster, D.G., et al. Kidney Int. 73(10):1151-1158(2008)
- Stove, V., et al. J. Virol. 79(17):11422-11433(2005)
- Morel, N. Biol. Cell 95(7):453-457(2003)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Bovine, Pig
This ATP6V1H antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 400-426 amino acids from the C-terminal region of human ATP6V1H.
51606
V-type proton ATPase subunit H
ATP6V1H
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
56 kDa
Q9UI12
12643371
This antibody is purified through a protein A column, followed by peptide affinity purification.
Obesity,Signal Transduction
Q9UI12
Optimal dilutions for each application to be determined by the researcher.