ProSci

GPT2 Antibody

Product Code:
 
PSI-59-601
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
1 / 2
Western blot analysis in HepG2 cell line lysates (35ug/lane).
2 / 2
Western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).
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Western blot analysis in HepG2 cell line lysates (35ug/lane).
Western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).

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PSI-59-601-400ul400ul£626.00
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Further Information

Additional Names:
Alanine aminotransferase 2, ALT2, Glutamate pyruvate transaminase 2, GPT 2, Glutamic--alanine transaminase 2, Glutamic--pyruvic transaminase 2, GPT2, AAT2, ALT2
Application Note:
For WB starting dilution is: 1:1000
Background:
GPT (MIM 138200) and GPT2 (EC 2.6.1.2), also known as alanine transaminases, are pyridoxal enzymes that catalyze the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. By mediating the conversion of these 4 major intermediate metabolites, these transaminases have roles in gluconeogenesis and in amino acid metabolism.
Background References:
  • Glinghammar, B., et al. Int. J. Mol. Med. 23(5):621-631(2009)
  • Fraser, A., et al. Hepatology 46(1):158-165(2007)
  • Ding, Y., et al. World J. Gastroenterol. 12(43):7038-7041(2006)
  • Martin, J., et al. Nature 432(7020):988-994(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GPT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-44 amino acids from the N-terminal region of human GPT2.
NCBI Gene ID #:
84706
NCBI Official Name:
Alanine aminotransferase 2
NCBI Official Symbol:
GPT2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
58 kDa
Protein Accession #:
Q8TD30
Protein GI Number:
74730602
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q8TD30
User NOte:
Optimal dilutions for each application to be determined by the researcher.