ProSci

MCCC1 Antibody

Product Code:
 
PSI-62-005
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in mouse liver tissue lysates (15ug/lane).This demonstrates the detected MCCC1 protein (arrow).
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Western blot analysis in mouse liver tissue lysates (15ug/lane).This demonstrates the detected MCCC1 protein (arrow).

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PSI-62-005-400ul400ul£626.00
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This product comes from: United States.
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Further Information

Additional Names:
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial, MCCase subunit alpha, 3-methylcrotonyl-CoA carboxylase 1, 3-methylcrotonyl-CoA carboxylase biotin-containing subunit, 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha, MCCC1, MCCA
Application Note:
For WB starting dilution is: 1:1000
Background:
MCCC1 is the large subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA.
Background References:
  • Holzinger, A., et al. Hum. Mol. Genet. 10(12):1299-1306(2001)
  • Obata, K., et al. Genomics 72(2):145-152(2001)
  • Baumgartner, M.R., et al. J. Clin. Invest. 107(4):495-504(2001)
  • Gallardo, M.E., et al. Am. J. Hum. Genet. 68(2):334-346(2001)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MCCC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 397-425 amino acids from the Central region of human MCCC1.
NCBI Gene ID #:
56922
NCBI Official Name:
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial
NCBI Official Symbol:
MCCC1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
80 kDa
Protein Accession #:
Q96RQ3
Protein GI Number:
108861983
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q96RQ3
User NOte:
Optimal dilutions for each application to be determined by the researcher.