ProSci

MTHFS Antibody

Product Code:
 
PSI-60-002
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in mouse spleen tissue lysates (35ug/lane).
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Western blot analysis in mouse spleen tissue lysates (35ug/lane).

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PSI-60-002-400ul400ul£626.00
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Further Information

Additional Names:
5-formyltetrahydrofolate cyclo-ligase,10-methenyl-tetrahydrofolate synthetase, MTHFS, Methenyl-THF synthetase, MTHFS
Application Note:
For WB starting dilution is: 1:1000
Background:
MTHFS contributes to tetrahydrofolate metabolism. Helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids.
Background References:
  • Kelemen, L.E., et al. Cancer Epidemiol. Biomarkers Prev. 19(7):1822-1830(2010)
  • Hazra, A., et al. Cancer Causes Control 21(3):331-345(2010)
  • Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
  • Wu, D., et al. Cancer Res. 69(18):7294-7301(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MTHFS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-159 amino acids from the C-terminal region of human MTHFS.
NCBI Gene ID #:
100528021, 10588
NCBI Official Name:
5-formyltetrahydrofolate cyclo-ligase
NCBI Official Symbol:
MTHFS
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
23 kDa
Protein Accession #:
P49914
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
P49914
User NOte:
Optimal dilutions for each application to be determined by the researcher.