ProSci

RANBP17 Antibody

Product Code:
 
PSI-59-937
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in mouse testis tissue lysates (35ug/lane).
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Western blot analysis in mouse testis tissue lysates (35ug/lane).

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PSI-59-937-400ul400ul£626.00
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Further Information

Additional Names:
Ran-binding protein 17, RANBP17
Application Note:
For WB starting dilution is: 1:1000
Background:
The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors.
Background References:
  • Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
  • Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
  • Kutay, U., et al. J. Biol. Chem. 275(51):40163-40168(2000)
  • Koch, P., et al. Biochem. Biophys. Res. Commun. 278(1):241-249(2000)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This RANBP17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-175 amino acids from the N-terminal region of human RANBP17.
NCBI Gene ID #:
64901
NCBI Official Name:
Ran-binding protein 17
NCBI Official Symbol:
RANBP17
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
124 kDa
Protein Accession #:
Q9H2T7
Protein GI Number:
17368945
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9H2T7
User NOte:
Optimal dilutions for each application to be determined by the researcher.