ProSci

RGS4 Antibody

Product Code:
 
PSI-63-686
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis of RGS4 Antibody in MDA-MB231 cell line lysates (35ug/lane)
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Western blot analysis of RGS4 Antibody in mouse brain tissue lysates (35ug/lane)
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Western blot analysis of RGS4 Antibody in MDA-MB231 cell line lysates (35ug/lane)
Western blot analysis of RGS4 Antibody in mouse brain tissue lysates (35ug/lane)

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PSI-63-686-400ul400ul£626.00
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This product comes from: United States.
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Further Information

Additional Names:
Regulator of G-protein signaling 4, RGP4, RGS4, RGS4
Application Note:
For WB starting dilution is: 1:1000
Background:
Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37% identical to RGS1 and 97% identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm.
Background References:
  • Heximer,S.P., et.al., Proc. Natl. Acad. Sci. U.S.A. 94 (26), 14389-14393 (1997)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rat, Rabbit, Monkey, Bovine
Immunogen:
This RGS4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-174 amino acids from the Central region of human RGS4.
NCBI Gene ID #:
5999
NCBI Official Name:
Regulator of G-protein signaling 4
NCBI Official Symbol:
RGS4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
23 kDa
Protein Accession #:
P49798
Protein GI Number:
1710146
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P49798
User NOte:
Optimal dilutions for each application to be determined by the researcher.