ProSci

PTP4A1 Antibody

Product Code:
 
PSI-58-807
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
1 / 2
Western blot analysis in mouse bladder tissue lysates (35ug/lane).
2 / 2
Western blot analysis of PTP4A1 using rabbit polyclonal PTP4A1 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PTP4A1 gene.
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Western blot analysis in mouse bladder tissue lysates (35ug/lane).
Western blot analysis of PTP4A1 using rabbit polyclonal PTP4A1 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PTP4A1 gene.

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PSI-58-807-400ul400ul£626.00
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Further Information

Additional Names:
Protein tyrosine phosphatase type IVA 1, PTP(CAAXI), Protein-tyrosine phosphatase 4a1, Protein-tyrosine phosphatase of regenerating liver 1, PRL-1, PTP4A1, PRL1, PTPCAAX1
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This tyrosine phosphatase is a nuclear protein, but may primarily associate with plasma membrane. The surface membrane association of this protein depends on its C-terminal prenylation. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which implicated its role in the tumorigenesis. Studies in rat suggested that this gene may be an immediate-early gene in mitogen-stimulated cells. [provided by RefSeq].
Background References:
  • Johnatty, S.E., et al. PLoS Genet.(7), E1001016 (2010) :
  • Skinner, A.L., et al. Biochemistry 48(20):4262-4272(2009)
  • Luo, Y., et al. Biochemistry 48(8):1838-1846(2009)
  • Min, S.H., et al. Oncogene 28(4):545-554(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Monkey, Rat
Immunogen:
This PTP4A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-168 amino acids from the C-terminal region of human PTP4A1.
NCBI Gene ID #:
7803
NCBI Official Name:
Protein tyrosine phosphatase type IVA 1
NCBI Official Symbol:
PTP4A1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
20 kDa
Protein Accession #:
Q93096
Protein GI Number:
68566217
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q93096
User NOte:
Optimal dilutions for each application to be determined by the researcher.