Further Information
Thyrotroph embryonic factor, TEF, KIAA1655
For WB starting dilution is: 1:1000
Thyrotroph embryonic factor (TEF), a transcription factor,
is a member of the PAR (proline and acidic amino acid-rich)
subfamily of basic region/leucine zipper (bZIP) transcription
factors. It is expressed in a broad range of cells and tissues in
adult animals, however, during embryonic development, TEF
expression appears to be restricted to the developing anterior
pituitary gland, coincident with the appearance of
thyroid-stimulating hormone, beta (TSHB). Indeed, TEF can bind to,
and transactivate the TSHB promoter. It shows homology (in the
functional domains) with other members of the PAR-bZIP subfamily of
transcription factors, which include albumin D box-binding protein
(DBP), human hepatic leukemia factor (HLF) and chicken vitellogenin
gene-binding protein (VBP); VBP is considered the chicken homologue
of TEF. Different members of the subfamily can readily form
heterodimers, and share DNA-binding, and transcriptional regulatory
properties. Alternatively spliced transcript variants encoding
different isoforms have been found for this gene. [provided by
RefSeq].
- Kripke, D.F., et al. Psychiatry Investig 7(1):36-42(2010)
- Inukai, T., et al. Blood 105(11):4437-4444(2005)
- Collins, J.E., et al. Genome Biol.(10), R84 (2004) :
- Newman, J.R., et al. Science 300(5628):2097-2101(2003)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Chicken, Rat
This TEF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 213-240 amino acids from the C-terminal region of human TEF.
7008
Thyrotroph embryonic factor
TEF
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
33 kDa
Q10587
51338730
This antibody is purified through a protein A column, followed by peptide affinity purification.
Signal Transduction
Q10587
Optimal dilutions for each application to be determined by the researcher.